Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9233968, 21
    Show/Hide
 PubChem ID
CID: 118638430
Canonical SMILES
Cc1ccc(F)c(c1)C(=O)Nc1cccc(c1)C#Cc1ccc2nc(N)cn2n1
    Show/Hide
Compound Formula C22H16FN5O
Compound Structure
Protein Name
 Protein Info 
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000749 HUVEC-C
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1121 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 88 nM