Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9193726, 51
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 PubChem ID
CID: 90073656
Canonical SMILES
C[C@@H]([C@@H]1CC[C@@H](O1)c1ccc(c(F)c1)C(F)(F)F)N1CCn2c(ccc(-n3cnc(C)c3)c2=O)C1=O
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Compound Formula C25H24F4N4O3
Compound Structure
Protein Name
 Protein Info 
Presenilin-1
Protein Classification
Ion channel
>
Other ion channel
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Miscellaneous ion channel
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Presenilin ER Ca2+ leak channel family
Uniprot ID
P49768
Gene Name
PSEN1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 8.35 nM
   TI
   LI
   LO
   TS