Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9193726, 15
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 PubChem ID
CID: 90074100
Canonical SMILES
Cc1cn(cn1)-c1ccc2C(=O)N(C[C@H]3CCC[C@@H](O3)c3ccc(cc3)C(F)(F)F)CCn2c1=O
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Compound Formula C25H25F3N4O3
Compound Structure
Protein Name
 Protein Info 
Presenilin-1
Protein Classification
Ion channel
>
Other ion channel
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Miscellaneous ion channel
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Presenilin ER Ca2+ leak channel family
Uniprot ID
P49768
Gene Name
PSEN1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 29.9 nM
   TI
   LI
   LO
   TS