Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9193726, 46
    Show/Hide
 PubChem ID
CID: 90074054
Canonical SMILES
Cc1cn(cn1)-c1ccc2C(=O)N(C[C@@H]3CC[C@@H](O3)c3ccc(OC(F)(F)F)cc3)CCn2c1=O
    Show/Hide
Compound Formula C24H23F3N4O4
Compound Structure
Protein Name
 Protein Info 
Presenilin-1
Protein Classification
Ion channel
>
Other ion channel
>
Miscellaneous ion channel
>
Presenilin ER Ca2+ leak channel family
Uniprot ID
P49768
Gene Name
PSEN1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 60.3 nM
   TI
   LI
   LO
   TS