Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9193726, 37
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 PubChem ID
CID: 90073994
Canonical SMILES
CC(C)c1cc(O[C@@H]2CC[C@H]2N2CCn3c(ccc(-n4cnc(C)c4)c3=O)C2=O)ccc1Cl
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Compound Formula C25H27ClN4O3
Compound Structure
Protein Name
 Protein Info 
Presenilin-1
Protein Classification
Ion channel
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Other ion channel
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Miscellaneous ion channel
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Presenilin ER Ca2+ leak channel family
Uniprot ID
P49768
Gene Name
PSEN1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 158 nM
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