Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9193726, 64
    Show/Hide
 PubChem ID
CID: 121596857
Canonical SMILES
C[C@@H]1C[C@@H](CN2CCn3c(ccc(-n4cnc(C)c4)c3=O)C2=O)O[C@H]1c1ccc(cc1)C(F)(F)F
    Show/Hide
Compound Formula C25H25F3N4O3
Compound Structure
Protein Name
 Protein Info 
Presenilin-1
Protein Classification
Ion channel
>
Other ion channel
>
Miscellaneous ion channel
>
Presenilin ER Ca2+ leak channel family
Uniprot ID
P49768
Gene Name
PSEN1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 73.5 nM
   TI
   LI
   LO
   TS