Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9193726, 52
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 PubChem ID
CID: 90073958
Canonical SMILES
COc1cc(ccc1[C@H]1CC[C@H](O1)[C@H](C)N1CCn2c(ccc(-n3cnc(C)c3)c2=O)C1=O)C(F)(F)F
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Compound Formula C26H27F3N4O4
Compound Structure
Protein Name
 Protein Info 
Presenilin-1
Protein Classification
Ion channel
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Other ion channel
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Miscellaneous ion channel
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Presenilin ER Ca2+ leak channel family
Uniprot ID
P49768
Gene Name
PSEN1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS