Brief Information of the Compound and Protein
Compound Name
US9186360, 99
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PubChem ID
CID: 53391153
SID: 125319335
Canonical SMILES
Cn1c2oc(Cl)c(CC(=O)Nc3nc(cs3)-c3ccc(c(F)c3)C(F)(F)F)c2c(=O)n(C)c1=O
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Compound Formula C20H13ClF4N4O4S
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily V member 4
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
Q9HBA0
Gene Name
TRPV4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1470 nM
   TI
   LI
   LO
   TS