Brief Information of the Compound and Protein
Compound Name
US9163012, 68
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Canonical SMILES
NC(=O)[C@]12CC3CC(C1)[C@@H](OC(=O)N1CC[C@@H](n4c(=O)[nH]c5cccc(Cl)c54)C1)C(C3)C2
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Compound Formula C23H27ClN4O4
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
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Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 0.46 nM
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