Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9163012, 28
    Show/Hide
Canonical SMILES
O[C@@]12CC3CC(C1)[C@H](OC(=O)N1CC[C@H](C1)Nc1ncc(Cl)cc1[N+]([O-])=O)C(C3)C2
    Show/Hide
Compound Formula C20H25ClN4O5
Compound Structure
Protein Name
 Protein Info 
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 3.69 nM
   TI
   LI
   LO
   TS