Brief Information of the Compound and Protein
Compound Name
US9163012, 70
    Show/Hide
Canonical SMILES
Cn1c2cc(ccc2n([C@H]2CCN(C2)C(=O)O[C@H]2C3CC4CC2C[C@](C4)(C3)C(N)=O)c1=O)C#N
    Show/Hide
Compound Formula C25H29N5O4
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 3.14 nM
   TI
   LI
   LO
   TS