Brief Information of the Compound and Protein
Compound Name
US9163011, 24
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PubChem ID
CID: 71529375
SID: 163522937
Canonical SMILES
C[C@@]1(N=C(N)OCC1(F)F)c1nc(NC(=O)c2ncc(OCC(F)F)cc2Cl)ccc1F
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Compound Formula C18H15ClF5N5O3
Compound Structure
Protein Name
Amyloid-beta precursor protein
Protein Classification
Membrane receptor
Uniprot ID
P05067
Gene Name
APP
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 250 nM
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