Brief Information of the Compound and Protein
Compound Name
US9163011, 1
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PubChem ID
CID: 71273895
SID: 163522735
Canonical SMILES
Cc1cc(cnc1C(=O)Nc1ccc(F)c(n1)[C@@]1(C)N=C(N)OCC1(F)F)C#N
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Compound Formula C18H15F3N6O2
Compound Structure
Protein Name
Amyloid-beta precursor protein
Protein Classification
Membrane receptor
Uniprot ID
P05067
Gene Name
APP
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 7 nM
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