Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9447092, 1
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 PubChem ID
CID: 71454279
SID: 163475538
Canonical SMILES
Cc1nn(C)cc1-c1nc2c(N3CCN(Cc4ccc(Cl)cc4)CC3)c(Cl)cnc2[nH]1
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Compound Formula C22H23Cl2N7
Compound Structure
Protein Name
 Protein Info 
Aurora kinase A
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
>
Other protein kinase AUR family
Uniprot ID
O14965
Gene Name
AURKA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 38 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 7.5 nM