Brief Information of the Compound and Protein
Compound Name
4-Pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-yl-piperazine-1-carbothioic acid [4-(pyrimidin-2-ylsulfamoyl)-phenyl]-amide
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PubChem ID
CID: 59020502
Canonical SMILES
O=S(=O)(Nc1ncccn1)c1ccc(NC(=S)N2CCN(c3ncnc4c3sc3ncccc34)CC2)cc1
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Compound Formula C24H21N9O2S3
Compound Structure
Protein Name
Platelet-derived growth factor receptor alpha
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P16234
Gene Name
PDGFRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000207 MIA PaCa-2 Homo sapiens (Human)  1
1
IC50 > 50000 nM
   TI
   LI
   LO
   TS
CL000206 PANC-1 Homo sapiens (Human)  1
1
IC50 > 50000 nM
   TI
   LI
   LO
   TS