Brief Information of the Compound and Protein
Compound Name
4-(6,7-dimethoxyquinazolin-4-yl)-N-(4-(N-pyrimidin-2-ylsulfamoyl)phenyl)piperazine-1-carbothioamide
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PubChem ID
CID: 59020517
Canonical SMILES
COc1cc2ncnc(N3CCN(C(=S)Nc4ccc(S(=O)(=O)Nc5ncccn5)cc4)CC3)c2cc1OC
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Compound Formula C25H26N8O4S2
Compound Structure
Protein Name
Platelet-derived growth factor receptor alpha
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P16234
Gene Name
PDGFRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000207 MIA PaCa-2 Homo sapiens (Human)  1
1
IC50 > 50000 nM
   TI
   LI
   LO
   TS
CL000206 PANC-1 Homo sapiens (Human)  1
1
IC50 > 50000 nM
   TI
   LI
   LO
   TS