Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-((3S)-3-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-7-methoxyquinazolin-6-yloxy)pyrrolidin-1-yl)prop-2-en-1-one
    Show/Hide
 PubChem ID
CID: 25126748
SID: 56451012
Canonical SMILES
C=CC(=O)N1CC[C@H](Oc2cc3c(Nc4ccc(OCc5ccccn5)c(Cl)c4)ncnc3cc2OC)C1
    Show/Hide
Compound Formula C28H26ClN5O4
Compound Structure
Protein Name
 Protein Info 
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 5 nM
   TI
   LI
   LO
   TS
2
IC50 = 10 nM
   TI
   LI
   LO
   TS