Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one
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 PubChem ID
CID: 5095
SID: 15221518
Canonical SMILES
CCCN(CCC)CCc1cccc2NC(=O)Cc12
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Compound Formula C16H24N2O
Compound Structure
Protein Name
 Protein Info 
D(2) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P14416
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 304 nM
   TI
   LI
   LO
   TS
2
Ki = 691.83 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 30 nM
   TI
   LI
   LO
   TS
2
EC50 = 89 nM
   TI
   LI
   LO
   TS
3
EC50 = 330 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 89 nM
   TI
   LI
   LO
   TS
2
EC50 = 330 nM
   TI
   LI
   LO
   TS
CL000035 NIH 3T3
 Cell Line Info 
Mus musculus (Mouse)  1
1
EC50 = 6.457 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 3.7 nM
2 Ki = 7.2 nM