Brief Information of the Compound and Protein
Compound Name
N1-(2,6-dichloro-3,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
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PubChem ID
CID: 88888615
Canonical SMILES
COc1cc(OC)c(Cl)c(N(CCNC(C)C)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1Cl
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Compound Formula C25H28Cl2N6O2
Compound Structure
Protein Name
Fibroblast growth factor receptor 3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P22607
Gene Name
FGFR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
IC50 = 74.13 nM
   TI
   LI
   LO
   TS
2
IC50 = 6165.95 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 9.772 nM