Brief Information of the Compound and Protein
Compound Name
N-(3,5-dimethoxyphenyl)-N-(3-((3S,5R)-3,5-dimethylpiperazin-1-yl)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
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PubChem ID
CID: 54591359
SID: 131341160
Canonical SMILES
COc1cc(OC)cc(N(CCCN2C[C@@H](C)N[C@@H](C)C2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1
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Compound Formula C29H37N7O2
Compound Structure
Protein Name
Receptor-type tyrosine-protein kinase FLT3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P36888
Gene Name
FLT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
IC50 = 4677.35 nM
   TI
   LI
   LO
   TS
2
IC50 = 8128.31 nM
   TI
   LI
   LO
   TS