Brief Information of the Compound and Protein
Compound Name
N-isopropyl-N'-[3-methoxy-5-(trideuteriomethoxy)phenyl]-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine
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PubChem ID
CID: 118014711
Canonical SMILES
[2H]C([2H])([2H])Oc1cc(OC)cc(N(CCNC(C)C)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1
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Compound Formula C25H30N6O2
Compound Structure
Protein Name
Fibroblast growth factor receptor 3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P22607
Gene Name
FGFR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
IC50 = 14.13 nM
   TI
   LI
   LO
   TS
2
IC50 = 7943.28 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.754 nM