Brief Information of the Compound and Protein
Compound Name
N-(3,5-dimethoxyphenyl)-N-((2-methylthiazol-4-yl)methyl)-3-(1-(2-(piperazin-1-yl)ethyl)-1H-pyrazol-4-yl)quinoxalin-6-amine
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PubChem ID
CID: 89447336
Canonical SMILES
COc1cc(OC)cc(N(Cc2csc(C)n2)c2ccc3ncc(-c4cnn(CCN5CCNCC5)c4)nc3c2)c1
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Compound Formula C30H34N8O2S
Compound Structure
Protein Name
Receptor-type tyrosine-protein kinase FLT3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P36888
Gene Name
FLT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
IC50 = 7762.47 nM
   TI
   LI
   LO
   TS
2
IC50 = 8912.51 nM
   TI
   LI
   LO
   TS