Brief Information of the Compound and Protein
Compound Name
2-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-2-methyl-1-(piperazin-1-yl)propan-1-one
    Show/Hide
PubChem ID
CID: 68208951
Canonical SMILES
COc1cc(OC)cc(N(CC2CC2)c2ccc3ncc(-c4cnn(C(C)(C)C(=O)N5CCNCC5)c4)nc3c2)c1
    Show/Hide
Compound Formula C31H37N7O3
Compound Structure
Protein Name
Receptor-type tyrosine-protein kinase FLT3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P36888
Gene Name
FLT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
IC50 = 4265.8 nM
   TI
   LI
   LO
   TS
2
IC50 = 5495.41 nM
   TI
   LI
   LO
   TS