Brief Information of the Compound and Protein
Compound Name
1-cyclopentyl-6-{(1R)-1-[3-(4-methylphenoxy)azetidin-1-yl]ethyl}-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
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PubChem ID
CID: 136613085
Canonical SMILES
Cc1ccc(OC2CN([C@H](C)c3nc4c(cnn4C4CCCC4)c(=O)[nH]3)C2)cc1
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Compound Formula C22H27N5O2
Compound Structure
Protein Name
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A
Protein Classification
Enzyme
>
Phosphodiesterase
>
Phosphodiesterase 9
>
Phosphodiesterase 9A
Uniprot ID
O76083
Gene Name
PDE9A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 222 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 67.1 nM