Brief Information of the Compound and Protein
Compound Name
6-{1-[3-(3,4-difluoro-2-methylphenoxy)azetidin-1-yl]ethyl}-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, trifluoroacetate salt
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PubChem ID
CID: 137304524
Canonical SMILES
Cc1c(OC2CN(C(C)c3nc4c(cnn4C4CCOCC4)c(=O)[nH]3)C2)ccc(F)c1F.O=C(O)C(F)(F)F
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Compound Formula C24H26F5N5O5
Compound Structure
Protein Name
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A
Protein Classification
Enzyme
>
Phosphodiesterase
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Phosphodiesterase 9
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Phosphodiesterase 9A
Uniprot ID
O76083
Gene Name
PDE9A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 78.7 nM
   TI
   LI
   LO
   TS