Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-{1-[3-(Pyrimidin-2-yloxy)azetidin-1-yl]ethyl}-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
    Show/Hide
 PubChem ID
CID: 136242452
SID: 163472016
Canonical SMILES
CC(c1nc2c(cnn2C2CCOCC2)c(=O)[nH]1)N1CC(Oc2ncccn2)C1
    Show/Hide
Compound Formula C19H23N7O3
Compound Structure
Protein Name
 Protein Info 
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A
Protein Classification
Enzyme
>
Phosphodiesterase
>
Phosphodiesterase 9
>
Phosphodiesterase 9A
Uniprot ID
O76083
Gene Name
PDE9A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 45.3 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 63 nM