Brief Information of the Compound and Protein
Compound Name
N-[4-methyl-3-[1-(6-methylpyridine-3-carbonyl)piperidin-4-yl]oxyphenyl]-4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)benzamide
    Show/Hide
PubChem ID
CID: 132546210
Canonical SMILES
CN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)Nc2ccc(C)c(OC3CCN(CC3)C(=O)c3ccc(C)nc3)c2)CC1
    Show/Hide
Compound Formula C33H38F3N5O3
Compound Structure
Protein Name
BCR/ABL p210 fusion protein
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
Uniprot ID
A1Z199
Gene Name
BCR/ABL FUSION
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
GI50 = 33 nM
   TI
   LI
   LO
   TS
CL000002 K-562 Homo sapiens (Human)  1
1
EC50 < 100 nM
   TI
   LI
   LO
   TS