Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(2-chloro-6-fluoroanilino)-1-ethyl-N-[3-fluoro-5-(trifluoromethyl)phenyl]-7,8-dihydro-[1,4]dioxino[2,3-e]benzimidazole-5-carboxamide
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 PubChem ID
CID: 89863688
Canonical SMILES
CCn1c(Nc2c(F)cccc2Cl)nc2cc(C(=O)Nc3cc(F)cc(c3)C(F)(F)F)c3OCCOc3c12
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Compound Formula C25H18ClF5N4O3
Compound Structure
Protein Name
 Protein Info 
Prostaglandin E synthase
Protein Classification
Enzyme
>
Isomerase
Uniprot ID
O14684
Gene Name
PTGES
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 54.69 nM
   TI
   LI
   LO
   TS
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 12.53 nM
   TI
   LI
   LO
   TS