Brief Information of the Compound and Protein
Compound Name
3-fluoro-4-[6-[2-hydroxy-2-(4-methyl-1-oxo-3H-2-benzofuran-5-yl)ethyl]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-2-yl]benzonitrile
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PubChem ID
CID: 118189049
Canonical SMILES
Cc1c2COC(=O)c2ccc1C(O)CN1CCc2nc(ncc2C1)-c1ccc(cc1F)C#N
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Compound Formula C25H21FN4O3
Compound Structure
Protein Name
ATP-sensitive inward rectifier potassium channel 1
Protein Classification
Ion channel
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Voltage-gated ion channel
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Potassium channels
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Inwardly rectifying potassium channel
Uniprot ID
P48048
Gene Name
KCNJ1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 463 nM
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