Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[(1S,2R,6R,7R)-3,3-dioxo-3lambda6-thia-4-azatricyclo[5.2.1.02,6]dec-8-en-4-yl]-2-(trifluoromethyl)benzonitrile
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 PubChem ID
CID: 24752898
SID: 49655635
Canonical SMILES
FC(F)(F)c1cc(ccc1C#N)N1C[C@H]2[C@@H]3C[C@@H](C=C3)[C@H]2S1(=O)=O
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Compound Formula C16H13F3N2O2S
Compound Structure
Protein Name
 Protein Info 
Androgen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 4
Uniprot ID
P10275
Gene Name
AR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000284 MDA-MB-453
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 219 nM
   TI
   LI
   LO
   TS
2
Ki = 12 nM
   TI
   LI
   LO
   TS