Brief Information of the Compound and Protein
Compound Name
2-[2-[2-(2,6-dichlorophenyl)propan-2-yl]-1-[4-(3-methylsulfonylphenyl)phenyl]imidazol-4-yl]propan-2-ol
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PubChem ID
CID: 117951324
Canonical SMILES
CC(C)(O)c1cn(c(n1)C(C)(C)c1c(Cl)cccc1Cl)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O
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Compound Formula C28H28Cl2N2O3S
Compound Structure
Protein Name
Oxysterols receptor LXR-beta
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group H
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Nuclear hormone receptor subfamily 1 group H member 3
Uniprot ID
P55055
Gene Name
NR1H2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1 Chlorocebus aethiops (Green monkey)  1
1
EC50 = 170 nM
   TI
   LI
   LO
   TS
CL000017 HeLa Homo sapiens (Human)  1
1
EC50 = 18 nM
   TI
   LI
   LO
   TS