Brief Information of the Compound and Protein
Compound Name
7-[2-[2-(2,4-dioxopyrimidin-1-yl)ethoxy]-4-fluorophenoxy]-5-fluoro-8-methylnaphthalene-2-carbonitrile
    Show/Hide
PubChem ID
CID: 129908647
Canonical SMILES
Cc1c(Oc2ccc(F)cc2OCCn2ccc(=O)[nH]c2=O)cc(F)c2ccc(cc12)C#N
    Show/Hide
Compound Formula C24H17F2N3O4
Compound Structure
Protein Name
Reverse transcriptase/RNaseH
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q72547
Gene Name
POL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000262 MT-2 Homo sapiens (Human)  2
1
EC50 = 31 nM
   TI
   LI
   LO
   TS
2
EC50 = 980 nM
   TI
   LI
   LO
   TS