Brief Information of the Compound and Protein
Compound Name
8-chloro-7-[2-[2-(2,4-dioxopyrimidin-1-yl)ethoxy]-4-fluorophenoxy]-5-fluoronaphthalene-2-carbonitrile
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PubChem ID
CID: 129908646
Canonical SMILES
Fc1ccc(Oc2cc(F)c3ccc(cc3c2Cl)C#N)c(OCCn2ccc(=O)[nH]c2=O)c1
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Compound Formula C23H14ClF2N3O4
Compound Structure
Protein Name
Reverse transcriptase/RNaseH
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q72547
Gene Name
POL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000262 MT-2 Homo sapiens (Human)  2
1
EC50 = 72 nM
   TI
   LI
   LO
   TS
2
EC50 = 1600 nM
   TI
   LI
   LO
   TS