Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[(1R,2S)-1-[1-(4-fluorophenyl)indazol-5-yl]oxy-1-(6-methoxypyridin-3-yl)propan-2-yl]cyclopropanecarboxamide
    Show/Hide
 PubChem ID
CID: 25013811
SID: 56357259
Canonical SMILES
COc1ccc(cn1)[C@@H](Oc1ccc2n(ncc2c1)-c1ccc(F)cc1)[C@H](C)NC(=O)C1CC1
    Show/Hide
Compound Formula C26H25FN4O3
Compound Structure
Protein Name
 Protein Info 
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000464 ChaGo-K-1
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 1.3 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.24 nM
   TI
   LI
   LO
   TS
3
IC50 = 0.4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.8 nM
2 IC50 = 6.3 nM
3 IC50 = 46 nM