Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-fluoro-4-N-[5-(methoxymethyl)-2-methylphenyl]-4-N-methyl-2-N-(3-methylsulfonyl-5-morpholin-4-ylphenyl)pyrimidine-2,4-diamine
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 PubChem ID
CID: 134154467
Canonical SMILES
COCc1ccc(C)c(c1)N(C)c1nc(Nc2cc(cc(c2)S(C)(=O)=O)N2CCOCC2)ncc1F
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Compound Formula C25H30FN5O4S
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase PAK 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase STE20 family
>
STE protein kinase PAKA subfamily
Uniprot ID
Q13153
Gene Name
PAK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000243 MCF-10A
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 3300 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 189 nM