Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[5-[[5-fluoro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]-methylamino]-2,4-dimethylphenyl]methanol
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 PubChem ID
CID: 134149733
Canonical SMILES
CN(c1cc(CO)c(C)cc1C)c1nc(Nc2ccc(cc2)N2CCN(C)CC2)ncc1F
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Compound Formula C25H31FN6O
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase PAK 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase STE20 family
>
STE protein kinase PAKA subfamily
Uniprot ID
Q13153
Gene Name
PAK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000243 MCF-10A
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 33 nM