Brief Information of the Compound and Protein
Compound Name
methyl (2R)-2-[2-[(4-chloro-3-pyridin-2-ylphenyl)carbamoyl]-5-methylquinolin-8-yl]propanoate
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PubChem ID
CID: 134147491
Canonical SMILES
COC(=O)[C@H](C)c1ccc(C)c2ccc(nc12)C(=O)Nc1ccc(Cl)c(c1)-c1ccccn1
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Compound Formula C26H22ClN3O3
Compound Structure
Protein Name
Protein smoothened
Protein Classification
Membrane receptor
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Frizzled family G protein-coupled receptor
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Smoothened receptor (frizzled family GPCR)
Uniprot ID
P56726
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000426 Shh Light II Mus musculus (Mouse)  1
1
IC50 = 270 nM
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