Brief Information of the Compound and Protein
Compound Name
N,3-bis(4-fluorophenyl)-5-pyridin-4-yl-3,4-dihydropyrazole-2-carboxamide
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PubChem ID
CID: 134136380
Canonical SMILES
Fc1ccc(NC(=O)N2N=C(CC2c2ccc(F)cc2)c2ccncc2)cc1
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Compound Formula C21H16F2N4O
Compound Structure
Protein Name
Voltage-dependent T-type calcium channel subunit alpha-1H
Protein Classification
Ion channel
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Voltage-gated ion channel
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Voltage-gated calcium channel
Uniprot ID
O95180
Gene Name
CACNA1H
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 220 nM
   TI
   LI
   LO
   TS
2
IC50 = 1700 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 33 nM
   TI
   LI
   LO
   TS