Brief Information of the Compound and Protein
Compound Name
(2R,3S)-5-[3-[[5-(2,6-dimethylpyridin-3-yl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
    Show/Hide
PubChem ID
CID: 121304542
Canonical SMILES
Cc1ccc(-c2nnc(SCCCN3CC[C@]4(C[C@@H]4c4ccc(cc4)C(F)(F)F)C3)n2C)c(C)n1
    Show/Hide
Compound Formula C26H30F3N5S
Compound Structure
Protein Name
Potassium voltage-gated channel subfamily H member 2
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Potassium channels
>
Voltage-gated potassium channel
Uniprot ID
Q12809
Gene Name
KCNH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 933.25 nM
   TI
   LI
   LO
   TS