Brief Information of the Compound and Protein
Compound Name
 Compound Info 
9-ethyl-6,6-dimethyl-8-[1-(oxane-4-carbonyl)-3,6-dihydro-2H-pyridin-4-yl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile
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 PubChem ID
CID: 127036344
Canonical SMILES
CCc1cc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2cc1C1=CCN(CC1)C(=O)C1CCOCC1
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Compound Formula C32H33N3O3
Compound Structure
Protein Name
 Protein Info 
ALK tyrosine kinase receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
Q9UM73
Gene Name
ALK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000320 NCI-H3122
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 126 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.7 nM
2 IC50 = 18 nM