Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1256580-46-7
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 PubChem ID
CID: 49806720
SID: 103778663
Canonical SMILES
CCc1cc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2cc1N1CCC(CC1)N1CCOCC1
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Compound Formula C30H34N4O2
Compound Structure
Protein Name
 Protein Info 
ALK tyrosine kinase receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
Q9UM73
Gene Name
ALK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000320 NCI-H3122
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 19 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  4
1
IC50 = 0.59 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.96 nM
   TI
   LI
   LO
   TS
3
IC50 = 1.5 nM
   TI
   LI
   LO
   TS
4
IC50 = 3.9 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.56 nM
2 IC50 = 1.9 nM
3 IC50 = 2.07 nM
4 IC50 = 5.3 nM
5 IC50 = 11.5 nM
6 IC50 = 15.2 nM
7 IC50 = 1030 nM