Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(4-(Trifluoromethyl)phenyl)-7,8-dihydro-5H-thiopyrano-[4,3-d]pyrimidin-4-ol
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 PubChem ID
CID: 135418940
SID: 99378294
Canonical SMILES
FC(F)(F)c1ccc(cc1)-c1nc2CCSCc2c(=O)[nH]1
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Compound Formula C14H11F3N2OS
Compound Structure
Protein Name
 Protein Info 
Poly [ADP-ribose] polymerase tankyrase-2
Protein Classification
Enzyme
>
Transferase
Uniprot ID
Q9H2K2
Gene Name
TNKS2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 5.3 nM
   TI
   LI
   LO
   TS
2
IC50 = 17 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 2.1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.1 nM
2 IC50 = 3.6 nM
3 IC50 = 4 nM
4 IC50 = 5 nM
5 IC50 = 5.3 nM
6 IC50 = 9.6 nM
7 IC50 = 15 nM
8 IC50 = 17 nM
9 Kd = 10 nM