Brief Information of the Compound and Protein
Compound Name
3,7-bis(1H-pyrazol-4-yl)-5H-indeno[1,2-b]indol-10-one
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PubChem ID
CID: 127050278
Canonical SMILES
O=C1c2ccc(cc2-c2[nH]c3cc(ccc3c12)-c1cn[nH]c1)-c1cn[nH]c1
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Compound Formula C21H13N5O
Compound Structure
Protein Name
Receptor-type tyrosine-protein kinase FLT3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P36888
Gene Name
FLT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
IC50 = 34 nM
   TI
   LI
   LO
   TS
2
IC50 = 55 nM
   TI
   LI
   LO
   TS