Brief Information of the Compound and Protein
Compound Name
10-oxo-3-(1H-pyrazol-4-yl)-5H-indeno[1,2-b]indole-7-carbonitrile
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PubChem ID
CID: 127052114
Canonical SMILES
O=C1c2ccc(cc2-c2[nH]c3cc(ccc3c12)C#N)-c1cn[nH]c1
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Compound Formula C19H10N4O
Compound Structure
Protein Name
Receptor-type tyrosine-protein kinase FLT3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P36888
Gene Name
FLT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
IC50 = 96 nM
   TI
   LI
   LO
   TS
2
IC50 = 128 nM
   TI
   LI
   LO
   TS