Brief Information of the Compound and Protein
Compound Name
N-[4-methyl-3-[1-(pyridine-4-carbonyl)piperidin-4-yl]oxyphenyl]-3-(trifluoromethyl)benzamide
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PubChem ID
CID: 127043948
Canonical SMILES
Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1OC1CCN(CC1)C(=O)c1ccncc1
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Compound Formula C26H24F3N3O3
Compound Structure
Protein Name
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  9
1
GI50 = 40 nM
   TI
   LI
   LO
   TS
2
GI50 = 150 nM
   TI
   LI
   LO
   TS
3
GI50 = 190 nM
   TI
   LI
   LO
   TS
4
GI50 = 1030 nM
   TI
   LI
   LO
   TS
5
GI50 = 1050 nM
   TI
   LI
   LO
   TS
6
GI50 = 1060 nM
   TI
   LI
   LO
   TS
7
GI50 = 5310 nM
   TI
   LI
   LO
   TS
8
GI50 = 8240 nM
   TI
   LI
   LO
   TS
9
GI50 > 10000 nM
   TI
   LI
   LO
   TS