Brief Information of the Compound and Protein
Compound Name
N-(3-((1-Acryloylpiperidin-4-yl)oxy)-4-methylphenyl)-3-(trifluoromethyl)benzamide
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PubChem ID
CID: 127044108
Canonical SMILES
C=CC(=O)N1CCC(Oc2cc(NC(=O)c3cccc(C(F)(F)F)c3)ccc2C)CC1
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Compound Formula C23H23F3N2O3
Compound Structure
Protein Name
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
GI50 = 620 nM
   TI
   LI
   LO
   TS