Brief Information of the Compound and Protein
Compound Name
4-(4-Phenethyl-piperazin-1-yl)-6,7,8,9-tetrahydro-pyrimido[4,5-b]indolizine-10-carbonitrile
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PubChem ID
CID: 10407830
SID: 15425291
Canonical SMILES
N#Cc1c2CCCCn2c2c(ncnc12)N1CCN(CCc2ccccc2)CC1
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Compound Formula C23H26N6
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
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Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  1
1
IC50 = 8190 nM
   TI
   LI
   LO
   TS