Brief Information of the Compound and Protein
Compound Name
4-(4-benzylpiperazin-1-yl)-5,6-di(cycloheptyl)pyrrolo[3,2-d]pyrimidine-7-carbonitrile
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PubChem ID
CID: 127052889
Canonical SMILES
N#Cc1c(C2CCCCCC2)n(C2CCCCCC2)c2c(ncnc12)N1CCN(Cc2ccccc2)CC1
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Compound Formula C32H42N6
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
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Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  1
1
IC50 = 4680 nM
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