Brief Information of the Compound and Protein
Compound Name
4-(benzylamino)-6,7,8,9-tetrahydropyrimido[4,5-b]indolizine-10-carbonitrile
    Show/Hide
PubChem ID
CID: 917533
Canonical SMILES
N#Cc1c2CCCCn2c2c(NCc3ccccc3)ncnc12
    Show/Hide
Compound Formula C18H17N5
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  1
1
IC50 = 15800 nM
   TI
   LI
   LO
   TS