Brief Information of the Compound and Protein
Compound Name
4-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydropyrimido[4,5-b]indolizine-10-carbonitrile
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PubChem ID
CID: 10379829
SID: 15394694
Canonical SMILES
CN1CCN(CC1)c1ncnc2c(C#N)c3CCCCn3c12
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Compound Formula C16H20N6
Compound Structure
Protein Name
Multidrug resistance-associated protein 1
Protein Classification
Transporter
>
Primary active transporter
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ATP-binding cassette
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ABCC subfamily
Uniprot ID
P33527
Gene Name
ABCC1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000348 H69AR Homo sapiens (Human)  2
1
IC50 = 2870 nM
   TI
   LI
   LO
   TS
2
IC50 = 5060 nM
   TI
   LI
   LO
   TS